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Electronic prescribing of controlled substances (EPCS) technology enables clinicians to securely transmit prescriptions for controlled substances to a pharmacy (1). In 2018, the Substance Use Disorder Prevention that Promotes Opioid Recovery and Treatment for Patients and Communities Act (SUPPORT Act) mandated the prescribing of Schedule II, III, IV, or V controlled substances under Medicare Part D to be done using EPCS technology starting January 1, 2021 (2). This mandate was implemented and finalized through the Centers for Medicare & Medicaid Services (CMS) Calendar Year (CY) 2021 Physician Fee Schedule specifying appropriate exceptions and providing compliance flexibilities through January 1, 2022 (3). This brief provides national estimates of physicians’ use of EPCS technology in 2019 from the National Electronic Health Record Survey. These findings serve as basedline estimates upon which to examine the future impact of the Part D EPCS mandate going into effect. The brief also explores variation in the use of EPCS by physician characteristics; including practice size and ownership, physician specialty, geographic location, and frequency of a physician prescribing controlled substances.
Figure 1: Percent of office-based physicians that prescribe controlled substances and use EPCS technology, 2017-2019.

Table 1: Percent of office-based physicians that use paper and electronic methods to prescribe controlled and non-controlled substances, 2019.
| Method to Prescribe Controlled Substances | |||
|---|---|---|---|
| Electronic | Paper | ||
| Method to Prescribe Non-Controlled Substances Substances | Electronic | 43% | 47% |
| Paper | 1% | 9% | |
Figure 2: Percent of office-based physicians that use EPCS technology by frequency of prescribing controlled substances, 2019.

Table 2: Percent of office-based physicians that use EPCS technology by practice characteristics, 2019.
| Practice Characteristics | Use EPCS Technology (Among those who Prescribe Controlled Substances) |
|---|---|
| Practice Size | |
| 1 physician (reference) | 30% |
| 2-5 physicians | 49%* |
| 6-10 physicians | 46%* |
| 11 or more physicians | 52%* |
| Practice Ownership | |
| Physician/Physician Group (reference) | 36% |
| Insurance Company or Corporation | 59%* |
| Community Health Center | 61%* |
| Hospital | 58%* |
| Specialty Group | |
| Single Specialty (reference) | 42% |
| Multispecialty | 50%* |
| Medicare Physicians | |
| Treat Medicare Patients | 43% |
| Do Not Treat Medicare Patients | 48% |
| Medicaid Physicians | |
| Treat Medicaid Patients | 44% |
| Do Not Treat Medicaid Patients | 41% |
| Geographic Location | |
| Rural (reference) | 43% |
| Urban | 44% |
Figure 3: Percent of office-based physicians that use EPCS technology by practice ownership, 2017-2019.

Figure 4: Percent of office-based physicians that use EPCS technology by mental health care provider shortage area, 2019.

Table 3: Percent of office-based physicians that use EPCS technology by physician specialty, 2017-2019.
| Specialty |
Use EPCS Technology (Among specialties that frequently prescribe controlled substances ^) | |
|---|---|---|
| 2017 | 2019 | |
| All Physicians | 32% | 44%* |
| Primary Care | 32% | 51%* |
| Internal Medicine | 28% | 52%* |
| General or Family Practice | 34% | 47%* |
| Pediatrics | 34% | 59%* |
| Medical Specialty | 31% | 38% |
| Psychiatry | 36% | 68%* |
| Neurology | 30% | 66%* |
| Obstetrics & Gynecology | 32% | 46% |
| Surgical Specialty | 31% | 35% |
The percentage of physician prescribers of controlled substances that used EPCS technology increased between 2017 and 2019, from 32 to 44 percent. Most physicians—90%—prescribe controlled substances so the use of EPCS technology has room to grow. Increasing the use of EPCS is significant because similar to e-prescribing, EPCS has the potential to reduce provider burden and improve care coordination by preventing data entry errors, avoiding pharmacy calls to prescribers to clarify written instructions, and eliminating the need to coordinate and manage paper prescriptions between doctors, patients, pharmacies, and other care sites. These tools can also improve patient safety by alerting prescribers of potential drug interactions, inappropriate doses, allergies, and underlying patient conditions (1).
The rates of EPCS are lower than e-prescribing because the requirements to set up EPCS are more stringent. These requirements, estabilshed by the Drug Enforcement Agency, include identity proofing to verify a provider is authorized to prescribe controlled substances, two-factor authentication for health care providers who sign an EPCS prescription, as well as detailed recordkeeping requirements to assist with identifying auditable events and security breaches (4). It is likely partly due to these increased requirements, that among physicians who prescribe controlled substances, nearly half of these providers still relied on paper when prescribing controlled substances. Encouragingly, frequent prescribers of controlled substances reported using EPCS at higher rates compared to those who rarely prescribed controlled substances (60% vs. 24%). Nearly all psychiatrists and neurologists reported prescribing controlled substances. These specialties had the highest rates of reported EPCS use and also had large increases between 2017 and 2019. This likely reflects the value proposition for meeting the requirements for EPCS are higher for frequent prescribers of controlled substances.
This brief also identifies significant variation in use of EPCS by practice size and ownership. These findings indicate that costs and lack of financial support may be barriers to implementing EPCS technology for physicians with fewer resources (5). For example, only 30 percent of solo practitioners and 36 percent of providers in physician-owned practices reported using EPCS. These rates were lower compared to practices with 11 or more physicians (52%) and among practices owned by a corporation (59%) or hospital (58%). Similarly, physicians practicing in mental health provider shortage areas also reported using EPCS at lower rates compared to physicians practicing in non-shortage areas (31% vs. 50%). This indicates that areas of the country with fewer mental health providers, such as psychiatrists, may be lagging behind with use of EPCS. This is significant because an estimated 149 million Americans (45% of the US population) live in a mental health provider shortage area (7). In contrast, physicians working in community health centers or federally qualified health centers (FQHC)’s rates of engaging in EPCS was relatively high, doubling between 2017 and 2019 (increase from 26% to 61%). Previous research has shown that FQHCs are playing an increasing role in providing substance use disorder counseling and treatment services (6). The Health Resources & Services Administration has also funded organizations to provide training and technical assistance to support the adoption and advancement of health IT among FQHCs (8). This may explain the growth in EPCS use in comparison to other types of practices with fewer resources.
The results from this analysis show an increase in the use of EPCS between 2017 and 2019 in various physician practices bringing them closer to compliance of the federal mandate. This is consistent with more recent findings from Surescripts, which includes both hospital-based prescribers in addition to office-based prescribers (9). However, our analysis of 2019 office-based physician survey data suggests that works remains for all Part D providers to achieve full compliance under the SUPPORT Act, particularly practices with fewer resources and those serving vulnerable populations. The Office of the National Coordinator for Health IT has published the Health IT Playbook, which is a resource for health care providers and other stakeholders to use to optimize the safety and use of their electronic health records. The Playbook also includes educational materials for health care providers about the benefits of EPCS to support the appropriate prescribing of opioids and other controlled substances.
The Centers for Disease Control and Prevention’s National Center for Health Statistics conducts the National Electronic Health Records Survey (NEHRS) survey on an annual basis. Physicians included in this survey provide direct patient care in office-based practices and community health centers; excluded are those who do not provide direct patient care (radiologists, anesthesiologists, and pathologists). Additional documentation regarding the survey is here: https://www.cdc.gov/nchs/nehrs/index.html
The authors are with the Office of Technology, within the Office of the National Coordinator for Health Information Technology. The data brief was drafted under the direction of Mera Choi, Director of Technical Strategy and Analysis, and Vaishali Patel, the Data Analysis Branch Chief.
Johnson C. & Estrada M. (June 2022). Electronic Prescribing of Controlled Substances Among Office-Based Physicians, 2017-2019. ONC Data Brief, no.58. Office of the National Coordinator for Health Information Technology: Washington DC.
Appendix Table A1: Survey questions assessing hospital capabilities to enable patient electronic access to health information
| Question Text | Response Options |
|---|---|
| How frequently do you prescribe controlled substances? |
|
| How frequently are prescriptions for controlled substances sent electronically to the pharmacy? |
|
Appendix Table A2: Percent of office-based physicians that use paper and electronic methods to prescribe controlled and non-controlled substances, 2017.
| Method to Prescribe Controlled Substances | |||
|---|---|---|---|
| Electronic | Paper | ||
| Method to Prescribe Non-Controlled Substances | Electronic | 32% | 57% |
| Paper | <1% | 11% | |
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