HTI-4 Final Rule
ONC’s Health Data, Technology, and Interoperability: Electronic Prescribing, Real-Time Prescription Benefit and Electronic Prior Authorization (HTI-4) final rule finalizes certain proposals from the HTI-2 Patient Engagement, Information Sharing, and Public Health Interoperability proposed rule, including new and updated health IT certification criteria for electronic prior authorization, electronic prescribing, and real-time prescription benefit information.
The HTI-4 final rule also includes several related criteria for application programming interface (API) functionality and finalizes the adoption of additional standards for HHS that support the exchange of clinical and administrative information with payers. HTI-4 is published as part of the FY2026 CMS Hospital Inpatient Prospective Payment System (IPPS) final rule (CMS-1833-F).
The final rule is effective on October 1, 2025.
Blog and Information Session
HTI-4 Final Rule Information Session
ONC is held an information session on the HTI-4 final rule.
Presentation Slides [PDF – 409 KB]
HTI-2 Proposed Rule
Looking for content and materials from the HTI-2 proposed rule? View archived content