LEAP in Health IT Notice of Funding Opportunity

The Leading Edge Acceleration Projects (LEAP) in Health IT funding opportunity will address well-documented and fast emerging challenges that inhibit the development, use, and/or advancement of well-designed, interoperable health IT. It is expected to further a new generation of health IT development and inform the innovative implementation and refinement of standards, methods, and techniques for overcoming major barriers and challenges as they are identified.

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2025 Special Emphasis Notice (SEN)

ONC published a Special Emphasis Notice (SEN) under the Leading Edge Acceleration Projects (LEAP) in Health Information Technology (Health IT) funding opportunity NAP-AX-22-001. In fiscal year 2025, ONC seeks applications pursuant to the LEAP in Health IT notice of funding opportunity for projects that address one of the following areas of interests:

Area 1: Demonstrate readiness of FHIR®-based Subscriptions capability as a foundational health IT capability for improved interactivity with third-party applications.

Area 2: Identify and test innovative technical approaches that would inform future changes to the TEFCATM infrastructure to increase adoption of Individual Access Service (IAS).

The application period closed at 12:00 ET on April 25, 2025.

Special Emphasis Notice

View the full Special Emphasis Notice [PDF -339 KB]
View on Grants.gov

Informational Session

An informational session was held March 6, 2025 1:00 PM ET
Presentation Slides [PDF – 608 KB]

2024 Special Emphasis Notice (SEN)

ONC published a Special Emphasis Notice (SEN) under the Leading Edge Acceleration Projects (LEAP) in Health Information Technology (Health IT) funding opportunity NAP-AX-22-001. In 2024, ONC is particularly interested in applications whose specific aims address one of the following areas of interest:

Area 1: Develop innovative ways to improve healthcare-data quality to support responsible development of artificial intelligence (AI) tools in healthcare

Area 2: Accelerate adoption of health IT in behavioral health settings
The application period closed on July 12, 2024.

All Questions about this SEN should be submitted to ONC-LEAP@hhs.gov 
View Questions and Answers to the SEN

Special Emphasis Notice

View the full Special Emphasis Notice [370 KB]

Informational Session

An informational session was held on at 1:00 PM Eastern on May 21, 2024.
Slides from Informational Session [PDF – 15 MB]

2023 Special Emphasis Notice (SEN)

ONC published a Special Emphasis Notice (SEN) under the Leading Edge Acceleration Projects (LEAP) in Health Information Technology (Health IT) funding opportunity NAP-AX-22-001. In 2023, ONC was particularly interested in applications whose specific aims address one of the following areas of interest:

Area 1: Exploring the Use of Advanced Fast Health Care Interoperability Resources (FHIR®) Capabilities

Area 2: Identifying Data Quality Improvements for USCDI Data Elements
The application period closed on June 12, 2023.

Special Emphasis Notice

View the full Special Emphasis Notice [PDF – 476 KB]
View Responses to Questions about Special Emphasis Notice

Informational Session

An informational session was held on April 25, 2023. 
Presentation Slides [PDF – 14.6 MB]

2022 Notice of Funding Opportunity (NOFO)

ONC published a notice of funding opportunity (NOFO) under the Leading Edge Acceleration Projects (LEAP) in Health Information Technology (Health IT) funding opportunity NAP-AX-22-001. In 2022, ONC is particularly interested in applications whose specific aims address one of the following areas of interest:

Area 1: Address Health Equity and Social Determinants of Health (SDOH)Through Innovative, Open-Source Technology Tools, and Electronic Health Records (EHRs)

Area 2: Demonstrate the Use of Equity-Enhancing Patient-Generated Health Data (PGHD) for Clinical Care and Research

Notice of Funding Opportunity

View the full Notice of Funding Opportunity
Read Frequently Asked Questions
Read more about the opportunity on Grants.gov

Informational Session

An informational session was held on June 28, 2022. A video recording of the informational session is below.
Information Session Presentation Slides [PDF – 14.3 MB]

2021 Special Emphasis Notice (SEN)

The 2021 Special Emphasis Notice (SEN) asked for applications whose specific aims address one of the following areas of interest:

Area 1: Referral Management to Address Social Determinants of Health (SDOH) Aligned with Clinical Care

Area 2: Health IT Tools to Make Electronic Health Records (EHRs) Data Research – and Artificial Intelligence (AI)-Ready

Special Emphasis Notice

View the full Special Emphasis Notice [PDF- 295 KB]
Read Frequently Asked Questions

Read more about the opportunity on Grants.gov

Informational Session

An informational session was held on March 9, 2021. A video recording of the informational session and the presentation slides are below.
Information Session Presentation Slides [PDF – 945 KB]

2020 Special Emphasis Notice (SEN)

The 2020 Special Emphasis Notice asked for applications whose specific aims addressed one of the following areas of interest:

Area 1: Advancing Registry Infrastructure for a Modern API-based Health IT Ecosystem

Area 2: Cutting Edge Health IT Tools for Scaling Health Research

Area 3: Integrating Health Care and Human Services Data to Support Improved Outcomes

Resources:
View the full Special Emphasis Notice [PDF- 264 KB]
View recording of informational session
View session slides from informational session [PDF – 12 MB]

2019 Special Emphasis Notice (SEN)

The 2019 Special Emphasis Notice asked for applications whose specific aims addressed one of the following areas of interest:

Area 1: Standardization and Implementation of Scalable Health Level 7 International’s (HL7®) Fast Healthcare Interoperability Resources (FHIR®) Consent Resource 

Area 2: Design, Develop, and Demonstrate Enhanced Patient Engagement Technologies for Care and Research

Resources
View the full Special Emphasis Notice [PDF – 250 KB]
View recording of informational session

2018 Notice of Funding Opportunity (NOFO)

The 2018 Notice of Funding Opportunity was specifically interested in innovative solutions and breakthrough advances in the following areas of interest:

Area 1: Expanding the scope, scale, and utility of population-level data-focused application programming interfaces (APIs).

Area 2: Advancing Clinical Knowledge at the Point of Care.

Resources
View recording of informational session
View the full Notice of Funding Opportunity [PDF – 568 KB]